Central Pontine Myelinolysis in a Patient with Schizophrenia

Carine Nzodom, MD

Central pontine myelinolysis (CPM) was first described in 1959. Since then, many case reports and case series have been published about this topic. According to literature, the most common predisposing factor is hyponatremia and the most common presentation is encephalopathy. Unfortunately, the appropriate treatment of hyponatremia does not prevent this condition. The standard method of diagnosis is brain Magnetic resonance imaging (MRI). The typical radiological findings are hyperintense lesions in the central pons or associated extra pontine structures. Understanding the pathophysiology and recognizing the symptoms for CPM help identify the disease and therefore decrease its morbidity and mortality.

Login to read full article


Member Login